Also known as Siberian Ginseng, this adaptogen is the “king” of them all. There are more published studies on Eleuthero Root than any other herb (wow!). This superherb decreases fatigue by increasing your work and exercise capacity without the “crash” that comes with a morning cup of coffee. With this herb, you’ll also recover faster from acute stress and intense workouts. Check out the research for more interesting tidbits on what Eleuthero can do.
Cicero, A., Derosa, G., Brillante, R., Bernardi, R., Nascetti, S., & Gaddi, A. (2004). Effects Of Siberian Ginseng (Eleutherococcus Senticosus Maxim.) On Elderly Quality Of Life: A Randomized Clinical Trial. Archives of Gerontology and Geriatrics,38, 69-73. doi:10.1016/j.archger.2004.04.012
Conclusion: “E. senticosus safely improves some aspects of mental health and social functioning after 4 weeks of therapy, although these differences attenuate with continued use.”
Panossian, A., & Wikman, G. (2010). Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity. Pharmaceuticals,3(1), 188-224. doi:10.3390/ph3010188
Farnsworth N., Kinghorn A.D., Soejarto D.D., Waller D.P. Siberian Ginseng (Eleutherococcus senticosus): Current status as an adaptogen. In: Wagner H., Hikino H., Farnsworth N.R., editors. Economic and Medicinal Plant Research. Volume 1. Academic Press; London, UK: 1985. pp. 156–209.
Brekhman I.I. Eleutherococcus. Nauka; Leningrad, USSR: 1968. pp. 1–168.
Panossian A., Wikman G. Evidence-based efficacy of adaptogens in fatigue and molecular mechanisms relared to their stress-protective activity. In: Bonn K., editor. International Evidence–Based Complementary Medicine Conference; Armidale, Australia. 13-15 March; Armidale, Australia: University of New England; 2009. p. 10.
Ovodov Y.S., Frolova G.M., Nefedova M.Y., Elyakov G.B. Glycosides of Eleutherococcus senticosus. II. Structure of Eleutherosides A, B1, C and D. Khim. Prir. Soedin. 1965;1:63–64.
Norr H. Ph.D. Dissertation. Faculty of Chemistry and Pharmacy, Ludwig–Maximillians University; Munich, Germany: 1993. Phytochemical and pharmacological Investigations of the Adaptogens: Eleutherococcus senticosus, Ocimum sanctum, Codonopsis pilosula, Rhodiola rosea and Rhodiola crenulata; pp. 1–231
Jung C.H., Jung H., Shin Y.C., Shin Y.C., Park J.H., Jun C.Y., Kim H.M., Yim H.S., Shin M.G., Bae H.S., Kim S.H., Ko S.G. Eleutherococcus senticosus extract attenuates LPS-induced iNOS expression through the inhibition of Akt and JNK pathways in murine macrophage. J. Ethnopharmacol. 2007;113:183–187. doi: 10.1016/j.jep.2007.05.023
Kimura Y., Sumiyoshi M. Effects of various Eleutherococcus senticosus cortex on swimming time, natural killer activity and corticosterone level in forced swimming stressed mice. J. Ethnopharmacol. 2004;95:447–453. doi: 10.1016/j.jep.2004.08.027.
Barenboim G.M., Kozlova N.B. Application of Eleutherococcus extract for increasing of biological resistance of humans under influence of different environmental noxious factors. In: Barenboim G.M., editor. Eleutherococc. Strategy of Use and New Data of Fundamental Investigations. MedExport, Vneshtorgizdat; Moscow, USSR: 1985. pp. 7–20.
Bu Y., Jin Z.H., Park S.Y., Baek S., Rho S., Ha N., Park S.K., Kim H., Sun Y.K. Siberian ginseng reduces infarct volume in transient focal cerebral ischaemia in Sprague-Dawley rats. Phytother. Res. 2005;19:167–169. doi: 10.1002/ptr.1649.
Hartz A.J., Bentler S., Noyes R., Hoehns J., Logemann C., Sinift S., Butani Y., Wang W., Brake K., Ernst M., Kautzman H. Randomized controlled trial of Siberian Ginseng for chronic fatigue. Psychol. Med. 2004;34:51–61. doi: 10.1017/S0033291703008791
Some aspects of single doses of adaptogens (Eleutherococcus and Schizandra) In: Breikhman I.I., editor. Valeology: Diagnosis, Means and Practice in Health Care, International Collection of Scientific Papers. Far East Branch of the Academy of Science of the Russian Federation, Dalnauka; Vladivostok: 1995. pp. 105–117.
Winther K., Ranlov C., Rein E., Mehlsen J. Russian root (Siberian Ginseng) improves cognitive factions in middle-aged people, whereas Ginkgo biloba seems effective only in the elderly. J. Neurol. Sci. 1997;150:90.
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Cordyceps Militaris is an edible (when cooked) mushroom that is now safely and effectively cultivated, which seems to have various positive metabolic effects in humans due to its wide range of novel polysaccharides and because of the compound Cordycepin.